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Irregular, spontaneous, and often continual contractions of a muscle that is apparently at rest. Unlike the contractions of fibrillation, fasciculation is observable though the skin.

Minor fasciculation, such as that taking place in the eyelids, is common and is no cause for concern. However, constant fasciculation with weakness in the affected muscle indicates damage to the nerve cells in the spine that control the muscle, or to the nerve fibres that connect the spinal nerves to the muscle; motor neuron disease is one such disorder.

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