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Gianotti-crosti syndrome

A characteristic unharmful response of the skin to some viral infections, including Epstein Barr virus, hepatitis B infection, and Coxsackievirus.  In this condition a lumpy rash appears on the limbs, buttocks and face and last for several weeks.  The condition usually affects children between the ages of six months and twelve years.

Symptoms and signs

There can be no visible symptoms.  On the other hand, there can be a mild temperature and swelling of the lymph nodes in the groin and armpits that lasts for several months.  The liver can also become enlarged. 


Liver function tests and blood tests are undergone to investigate liver function and detect possible causative virus.  There is no exact treatment, but a mild topical corticosteroid cream can be given for itching.  The rash often fades in two to eight weeks.  

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