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Removal of part or all of the pancreas, which can be carried out as treatment for pancreatitis (inflammation of the pancreas).  In unusual cases, pancreatectomy is undergone as a treatment for insulinomas (insulin producing tumours).

Pancreatectomy can cause a deficiency of pancreatic hormones and digestive enzymes.  This situation can lead to diabetes mellitus, which needs to receive treatment with insulin therapy, and malabsorption, which needs oral supplements of pancreatin.  

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